Dihydrokawain
- Product Name
- Dihydrokawain
- CAS No.
- 587-63-3
- Chemical Name
- Dihydrokawain
- Synonyms
- MARINDININ;DIHYDROKAVAIN;DIHYDROKAWAIN;dihydro-kawai;DIHYDROKAWAIN;DIHYDROKAVAIN(P);7,8-Dihydrokavain;7,8-DIHYDROKAWAIN;(S)-(+)-7,8-Dihydrokavain;Dihydrokavain (7,8-Dihydrokawain
- CBNumber
- CB4314738
- Molecular Formula
- C14H16O3
- Formula Weight
- 232.27
- MOL File
- 587-63-3.mol
Dihydrokawain Property
- Melting point:
- 58-60°
- alpha
- D24 +31° (methanol)
- Boiling point:
- 314.44°C (rough estimate)
- Density
- 1.1649 (rough estimate)
- refractive index
- 1.5557 (estimate)
- storage temp.
- 2-8°C
- solubility
- DMF:25.0(Max Conc. mg/mL);107.62(Max Conc. mM)
DMSO:25.0(Max Conc. mg/mL);107.62(Max Conc. mM)
Ethanol:5.0(Max Conc. mg/mL);21.52(Max Conc. mM) - optical activity
- [α]/D 29±2°, c = 0.5 in methanol
- BRN
- 15362
- InChIKey
- VOOYTQRREPYRIW-LBPRGKRZSA-N
- LogP
- 1.950 (est)
Safety
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 41866
- Product name
- (S)-(+)-7,8-Dihydrokavain
- Purity
- analytical standard
- Packaging
- 5mg
- Price
- $539
- Updated
- 2022/05/15
- Product number
- 361778
- Product name
- Dihydrokawain
- Packaging
- 10mg
- Price
- $581
- Updated
- 2021/12/16
- Product number
- D450620
- Product name
- (+)-(S)-Dihydrokavain
- Packaging
- 1mg
- Price
- $185
- Updated
- 2021/12/16
- Product number
- FD76571
- Product name
- Dihydrokawain
- Packaging
- 10mg
- Price
- $250
- Updated
- 2021/12/16
- Product number
- PXT0000214
- Product name
- DIHYDROKAVAIN
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $713.26
- Updated
- 2021/12/16
Dihydrokawain Chemical Properties,Usage,Production
Chemical Properties
White-pale yellow powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the rhizome of kava-kava (Piper methysticum G. Forst).
Uses
(+)-(S)-Dihydrokavain is a kavalactone found in kava beverages consumed by South Pacific islanders. Furthermore, roots and extracts of the kava plant have been used in herbal medicine to treat sleep disturbances, as well as stress and anxiety.
Definition
ChEBI: Dihydrokavain is a member of 2-pyranones and an aromatic ether.
Application
Dihydrokavain is one of the six major kavalactones found in the kava plant; appears to contribute significantly to the anxiolytic effects of kava, based on a study in chicks.Used in herbal medicine to treat sleep disturbances, as well as stress and anxiety.
Preparation
Starting from 2,3-O-isopropylidene-D-glyceraldehyde (2) as chiral material, the naturally occurring (S)-(+)-dihydrokavain (1a) was synthesized by a procedure that involves a sonochemical Blaise reaction as the key step. The absolute configuration of (S)-(+)-dihydrokavain (1a) is demonstrated for the first time by total synthesis from a chiral source. Its opposite enantiomer, (R)-(–)-dihydrokavain (1b), was also synthesized after inversion of the chiral center in a Mitsunobu reaction.
A Total Synthesis of (+)- and (–)-Dihydrokavain with a Sonochemical Blaise Reaction as the Key Step
Dihydrokawain Preparation Products And Raw materials
Raw materials
Preparation Products
Dihydrokawain Suppliers
View Lastest Price from Dihydrokawain manufacturers
- Product
- Dihydrokavain 587-63-3
- Price
- US $0.00/mg
- Min. Order
- 20mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2020-04-27
- Product
- DIHYDROKAVAIN 587-63-3
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1kg,5kg,50kg
- Release date
- 2020-01-18